이병철 약력
■ Research Interest
1 Gene and cell therapy
2 Adult stem cells
3 CRISPR based editing
4 Organoid
5 In vivo gene editing
■ 학력
학사 2012 서울대학교 수의과대학 수의학
석∙박사 통합 2019 서울대학교 수의과대학 줄기세포생물학
■ Publications
- Lee BC*. Challenges and innovations in hematopoietic stem cell transplantation: Exploring bone marrow niches and new model systems. BMB Reports. 2024 Aug;57(8):352-362.
- Park HS*, Lee BC*, Chae DH, Yu A, Park JH, Heo J, Han MH, Cho K, Lee JW, Jung JW, Dunbar CE, Oh MK, Yu KR. Cigarette smoke impairs the hematopoietic supportive property of mesenchymal stem cells via the production of reactive oxygen species and NLRP3 activation. Stem Cell Res Ther. 2024 May 20;15(1):145.
- Lee BC*, Gin A*, Wu C, Singh S, Grice M, Mortlock R, Abraham A, Fan X, Zhou Y, Aljanahi A, Choi U, deRavin SS, Shin TH, Hong S, Dunbar CE. Impact of CRISPR/HDR-editing versus lentiviral transduction on long-term engraftment and clonal dynamics of HSPCs in rhesus macaques. Cell Stem Cell. 2024 Apr 4;31(4):455-466. (Correspondence)
- Lee BC*, Zhou Y*, Bresciani E, Ozkaya N, Dulau- Florea A, Carrington B, Shin TH, Baena V, Syed ZA, Hong SG, Zhen T, Calvo KR, Liu P, Dunbar CE. A RUNX1-FPDMM rhesus macaque model reproduces the human phenotype and predicts challenge to curative gene therapies. Blood. 2023 Jan 19;141(3):231-237.
- Lee BC, Lozano RJ, Dunbar CE. Understanding and Overcoming Adverse Consequences of Genome Editing on Hematopoietic Stem and Progenitor Cells. Mol Ther. 2021;29(11):3205-3218.
- Lee BC*, Lee JY*, Kim J*, Shin N, Yoo JM, Kang I, Kim JJ, Lee SE, Kim D, Choi SW, Hong BH, Kang KS. Oral administration of microbiome-friendly graphene quantum dots as therapy for colitis. 2d mater. 2021;8(2):025036.
- Lee BC*, Lee JY*, Kim J, Yoo JM, Kang I, Kim JJ, Shin N, Kim DJ, Choi SW, Kim D, Hong BH, Kang KS. Graphene quantum dots as anti-inflammatory therapy for colitis. Sci Adv. 2020;6(18):eaaz2630.
- Lee BC, Kim JJ, Lee JY, Kang I, Shin N, Lee SE, Choi SW, Cho JY, Kim HS, Kang KS. Disease-specific primed human adult stem cells effectively ameliorate experimental atopic dermatitis. Theranostics. 2019;9(12):3608.
- Lee BC*, Shin N*, Lee JY, Kang I, Kim JJ, Lee SE, Choi SW, Wester GA, Kang KS. MIS416 Enhances Therapeutic Functions of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Against Experimental Colitis by Modulating Systemic Immune Milieu. Front Immunol. 2018;9:1078.
- Kang I*, Lee BC*, Choi SW*, Lee JY, Kim JJ, Kim BE, Kim DH, Lee SE, Shin N, Seo Y, Kim HS, Kim DI, Kang KS. Donor-dependent Variation of Human Umbilical Cord Blood Mesenchymal Stem Cells in Response to Hypoxic Preconditioning and Amelioration of Limb Ischemia. Exp Mol Med. 2018;50(4):35.
