김근일 약력
■ Research Interest
1 Autophagy
2 Lysosome biogenesis
3 Transcriptional regulation of autophagy
4 PTM in cell signaling
5 Inflammation
■ Education
- 학사 1990 서울대학교
- 석사 1992 서울대학교 생화학
- 박사 1997 서울대학교 분자생물학
■ Selected Publications
- Choi SA, Kim J, Yu YS, Kim J, Kim SI, Bae H, Kwon J, Kim KI*, Baek SH* (*Co-corresponding). Dual mechanism of autophagy gene repression by PHF23 and therapeutic potential of its inhibition in protein aggregation disorders. Nucleic Acids Res. 2025 Nov 26;53(22):gkaf1317.
- Kim J, Yu YS, Kim KI*, Baek SH* (*Co-corresponding). Transcriptional repression of autophagy and lysosome biogenesis. Autophagy 2025 Feb 24:1-3.
- Kim J, Yu YS, Choi Y, Lee DH, Han S, Kwon J, Noda T, Ikawa M, Kim D, Kim H, Ballabio A, Kim KI*, Baek SH* (*Co-corresponding). USF2 and TFEB compete in regulating lysosomal and autophagy genes. Nat Commun. 2024 Sep 27;15(1):8334.
- 101. Yu YS, Kim H*, Kim KI*, Baek SH* (*Co-corresponding). Epigenetic regulation of autophagy by histone-modifying enzymes under nutrient stress. Cell Death Differ. 2023 Jun;30(6):1430- 1436.
- Park KC, Kim J, Lee A, Lim JS, Kim KI. Alleviation of imiquimod-induced psoriasis-like symptoms in Rorα-deficient mouse skin. BMB Rep. 2023 May;56(5):296-301.
- Lee Y, Kwon J, Jeong JH, Ryu JH, Kim KI. Kazinol C from Broussonetia kazinoki stimulates autophagy via endoplasmic reticulum stress-mediated signaling. Anim Cells Syst (Seoul). 2022 Jan 10;26(1):28-36.
- Kim D, Kim KI*, Baek SH* (*Co-corresponding). Roles of lysine-specific demethylase 1 (LSD1) in homeostasis and diseases. J Biomed Sci. 2021 Jun 4;28(1):41.
- Park KC*, Park JH*, Baek SH, Kim KI. Pontin-deficiency causes senescence in fibroblast cells and epidermal keratinocytes but induces apoptosis in cancer cells. Biochim Biophys Acta Mol Cell Res. 2020 Sep;1867(9):118740.
- Oh C, Jeong J, Oh SK, Baek SH, Kim KI. Inhibition of LSD1 phosphorylation alleviates colitis symptoms induced by dextran sulfate sodium. BMB Rep. 2020 Jul;53(7):385-390.
- Pyo KE, Kim CR, Lee M, Kim J-S, Kim KI*, Baek SH* (*Co-corresponding). ULK1 O-GlcNAcylation is crucial for activating VPS34 via ATG14L during autophagy initiation. Cell Reports 2018 Dec 4;25:2878–2890.
